• Tuesday June 2,2020


We explain what macromolecules are, their functions and their types of structure. In addition, natural and synthetic macromolecules.

A macromolecule can become composed of hundreds of thousands of atoms.
  1. What are macromolecules?

Macromolecules are huge molecules . They are generally the product of the union of smaller molecule units, known as monomers, through natural or artificial processes. That is to say, they are composed of thousands or hundreds of thousands of atoms .

These macromolecules can be of a biological nature, the result of the processes of living organisms, or synthetic, produced in laboratories by human hands.

The term macromolecules was coined in 1920 by Hermann Staudinger, Nobel Prize in Chemistry. Since then the term is used as more or less synonymous with polymers.

However, strictly speaking, this last term refers to chains of monomers that do not necessarily exceed 10 angstroms in diameter (10 -6 millimeters) and therefore have a size more similar to that of ordinary molecules. That is to say that not all polymers are macromolecules.

It can serve you: Nucleic Acids

  1. Functions of macromolecules

Macromolecules can have very different functions, depending on which one we are talking about. For example, glucose macromolecules are an energy source for living organisms.

A very different example is the DNA macromolecule, which is basically a cell memory device used when synthesizing proteins or when it comes to cell replication. That is, macromolecules do not have a single specific function.

  1. Structure of the macromolecules

DNA is a linear macromolecule.

Generally, the smaller units that compose them are joined together by covalent bonds, whether by hydrogen bonds, Van der Waals forces or hydrophobic interactions. In any case, they make up large molecule structures that contain thousands of atoms arranged in fixed sequences, resulting in compounds of the highest molecular weight.

In addition, depending on their structure, macromolecules can be:

  • Linear When they make long chains that repeat some order of monomers, linked together by head and tail.
  • Branched When each monomer can be attached to other chains, forming branches (such as trees) of different sizes or at a certain height of the main chain.

On the other hand, if in that chain the monomers are the same, repeating themselves, a homopolymer will be spoken, while if they alternate with other monomers it will be a copolymer. Number.

  1. Importance of macromolecules

The macromolecules differ from the rest of the natural and synthetic molecules in that they possess an enormous volume and molecular weight. As a consequence, its properties are more complex and useful than those of other molecules . For example, man-made polymers allow the creation of novel materials with unforeseen applications.

On the other hand, certain biological macromolecules perform complex tasks, either as a material and / or energy contributor to other processes, or as biochemical action mechanisms. Mica, as with insulin, the hormone regulating sugar in the human body, composed of 51 different amino acids.

  1. Natural macromolecules

Glucose is a natural macromolecule that serves as a source of energy.

Natural macromolecules are usually very specific compounds that fulfill vital functions. In some cases they function as metabolic inputs (such as carbohydrates) and in others they are structural molecules (such as lipids).

They are also fundamental actors of extremely complicated processes, such as DNA and RNA, that participate in cell replication or mitosis. Some simple examples of natural macromolecules are starch, cellulose, glycogen, fructose, glucose or lignin present in wood.

  1. Synthetic Macromolecules

On the contrary, synthetic molecules are, as the name implies, those artificially synthesized by humans, through various chemical processes in which the binding of monomers is controlled, enhanced or accelerated.

They are particularly important in the petrochemical and petroleum products industry, from which we obtain important organic materials of polymeric type, such as most plastics (polyethylene, PCV), synthetic fibers (polyester, nylon) or advanced materials (such as carbon nanotubes).

Continue with: Biomolecules

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